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Br-5MP-Propargyl

Protein Labeling

Br-5MP-Propargyl is a thiol-specific bioconjugation reagent designed for cysteine-specific protein labeling and modification. As a derivative of 5-Methylene pyrrolone (5MP), it enables reversible covalent bonding with cysteine residues. This compound features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating the attachment of azide-containing probes or tags to proteins. It is suitable for various applications in protein chemistry, including the study of protein interactions and the development of protein-based assays.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2468100-37-8
Applications	Protein Labeling
Formula	C₈H₆BrNO
Molecular Weight	212.04
SMILES	O=C(C(Br)=C1)N(CC#C)C1=C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.