Fig. 1 · Structure
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Br-Val-Ala-NH2-bicyclo1.1.1pentane-7-MAD-MDCPT
Drug-Linker Conjugate
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT functions as a drug-linker conjugate designed for targeted delivery in antibody-drug conjugate (ADC) applications. This compound combines a potent topoisomerase I inhibitor with a specialized linker, facilitating the efficient attachment to antibodies for enhanced specificity in cancer therapy. Its primary use lies in the development of novel ADCs aimed at improving therapeutic efficacy while minimizing off-target effects in research settings.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2857037-70-6 |
| Applications | Drug-Linker Conjugate |
| Formula | C36H38BrN5O9 |
| Molecular Weight | 764.62 |
| SMILES | BrCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.