Fig. 1 · Structure
Documents & Downloads
Bradanicline
α7 nAChR Agonist
Bradanicline is a highly selective agonist of the α7 nicotinic acetylcholine receptor (nAChR), exhibiting an EC50 of 17 nM and a Ki of 1.4 nM in human α7 nAChR assays. This compound is primarily utilized in research focused on cognitive disorders, providing insights into mechanisms of action and potential therapeutic applications for enhancing cognitive function.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 639489-84-2 |
| Applications | α7 nAChR Agonist |
| Formula | C22H23N3O2 |
| Molecular Weight | 361.44 |
| Synonyms | TC-5619 |
| SMILES | O=C(C1=CC2=CC=CC=C2O1)N[C@H]3[C@H](CC4=CC=CN=C4)N5CCC3CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.