Fig. 1 · Structure
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BrBzGCp2
GLO1 Inhibitor
BrBzGCp2 is a specific inhibitor of Glyoxalase 1 (GLO1), demonstrating a GC50 of 4.23 μM in HL-60 cells. This compound exhibits significant antitumor and neuroprotective properties, making it a valuable tool for research in cancer biology and neurodegenerative disease studies. Researchers can utilize BrBzGCp2 to explore the role of GLO1 in cellular stress responses and its potential implications in therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 166038-00-2 |
| Applications | GLO1 Inhibitor |
| Formula | C27H38BrN3O6S |
| Molecular Weight | 612.58 |
| Synonyms | S-p-Bromobenzylglutathione cyclopentyl diester |
| SMILES | O=C(NCC(OC1CCCC1)=O)[C@@H](NC(CC[C@H](N)C(OC2CCCC2)=O)=O)CSCC(C=C3)=CC=C3Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.