Fig. 1 · Structure

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BRD-9327

EfpA Inhibitor

BRD-9327 is an inhibitor of the EfpA transporter, identified for its binding in the outer vestibule, which does not fully obstruct the substrate pathway. This mechanism suggests that BRD-9327 interferes with the movement required for alternate access of the transporter. It holds promise for research applications in anti-tuberculosis studies, potentially aiding in the development of new therapeutic strategies against Mycobacterium tuberculosis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 443894-71-1
Applications EfpA Inhibitor
Formula C22H16BrNO4
Molecular Weight 438.27
SMILES
O=C(C1=CC=CC=C1Br)NC2=CC3=C(OCCO3)C=C2C(C4=CC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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