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BRD2889

GSTP1-ISCU Axis Modulator

BRD2889 is a GSTP1-ISCU axis modulator that serves as an analog of the alkaloid piperlongumine. It demonstrates significant biological activity in the context of pulmonary hypertension (PH) by effectively modulating this critical signaling pathway. Additionally, BRD2889 possesses a reactive alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, making it a valuable reagent for chemical biology applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	1415153-39-7
Applications	GSTP1-ISCU Axis Modulator
Formula	C₂₆H₂₅NO₆
Molecular Weight	447.48
SMILES	COC1=C(C=C(C=C1OC)/C=C/C(N2C(C(C#CC3=CC=C(C=C3)OC)=CCC2)=O)=O)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.