Fig. 1 · Structure
Documents & Downloads
BRD5529
CARD9-TRIM62 PPI Inhibitor
BRD5529 is a potent CARD9-TRIM62 protein-protein interaction inhibitor, demonstrating an IC50 value of 8.6 μM. This compound effectively inhibits CARD9 ubiquitinylation in vitro and exhibits favorable solubility characteristics. BRD5529 is suitable for research applications focused on inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1358488-78-4 |
| Applications | CARD9-TRIM62 PPI Inhibitor |
| Formula | C25H31N5O4 |
| Molecular Weight | 465.54 |
| SMILES | O=C(C1=CC(NC(C2=CC=C(C)C=C2)=O)=CN=C1N3CCC(N4CCCCC4)(C(N)=O)CC3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.