Fig. 1 · Structure
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BRD7389
RSK Inhibitor
BRD7389 is a specific inhibitor of the RSK family kinases, demonstrating IC50 values of 1.5 μM for RSK1, 2.4 μM for RSK2, and 1.2 μM for RSK3. This small-molecule compound effectively induces insulin expression in pancreatic α-cells, making it a valuable tool for research into diabetes and related metabolic disorders. Its selective action on RSK kinases allows for detailed exploration of their roles in cellular signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 376382-11-5 |
| Applications | RSK Inhibitor |
| Formula | C24H18N2O2 |
| Molecular Weight | 366.41 |
| SMILES | O=C(C(C=CC=C1)=C1C2=C(NCCC3=CC=CC=C3)C(N4)=O)C5=C2C4=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.