Fig. 1 · Structure
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BRD7586
Spcas9 Inhibitor
BRD7586 is a selective inhibitor of Streptococcus pyogenes Cas9 (SpCas9), demonstrating potent engagement with SpCas9 while sparing Cas12a. This compound enhances the specificity of SpCas9 at multiple genomic loci, making it a valuable tool for precision genome editing. BRD7586 inhibits SpCas9 activity across various delivery methods, supporting diverse research applications in genetic manipulation and CRISPR technology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 895460-70-5 |
| Applications | Spcas9 Inhibitor |
| Formula | C17H14ClN3O3S2 |
| Molecular Weight | 407.89 |
| SMILES | O=C(CCS(=O)(C1=CC=C(C=C1)Cl)=O)NC2=NC(C3=CC=NC=C3)=CS2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.