Brevinin-1

Catalog No.: A46845
Antimicrobial Peptide
Brevinin-1 is an antimicrobial peptide that targets microbial membranes. Isolated from the skin secretions of Rana esculenta, it demonstrates potent antibacterial and antifungal activity. Brevinin-1 is useful in microbiological studies and the development of novel antimicrobial treatments.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBrevinin-1 is an antimicrobial peptide that targets microbial membranes. Isolated from the skin secretions of Rana esculenta, it demonstrates potent antibacterial and antifungal activity. Brevinin-1 is useful in microbiological studies and the development of novel antimicrobial treatments.
Product Information
Catalog NumA46845
FormulaC121H202N28O26S2
Molecular Weight2529.20
CAS Number145963-49-1
SequencePhe-Leu-Pro-Val-Leu-Ala-Gly-Ile-Ala-Ala-Lys-Val-Val-Pro-Ala-Leu-Phe-Cys-Lys-Ile-Thr-Lys-Lys-Cys (Disulfide bridge:Cys18-Cys24)
Sequence shorteningFLPVLAGIAAKVVPALFCKITKKC (Disulfide bridge:Cys18-Cys24)
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CC(C)C)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H]5C(=O)N[C@@H](CCCCN)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(O)=O)CSSC5)[H])[H])=O)=O)CC(C)C)=O)C)=O)CCC3)C(C)C)=O)C(C)C)=O)CCCCN)=O)C)=O)C)=O)[C@H](CC)C)=O)=O)C)=O)CC(C)C)=O)[C@H](C)C)=O)CCC2
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