Fig. 1 · Structure
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Brigimadlin enantiomer
Brigimadlin Enantiomer
Brigimadlin enantiomer is a selective inhibitor of the MDM2 protein, which plays a critical role in regulating the p53 tumor suppressor pathway. This compound exhibits potent anti-cancer activity by promoting p53-mediated apoptosis in tumor cells. It is widely utilized in cancer research for investigating therapeutic strategies targeting MDM2-p53 interactions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3081532-91-1 |
| Applications | Brigimadlin Enantiomer |
| Formula | C31H25Cl2FN4O3 |
| Molecular Weight | 591.46 |
| Synonyms | BI 907828 enantiomer |
| SMILES | O=C(O)C1=C(C2=NN3C(C[C@]([H])([C@]3([C@H]([C@@]45C(NC6=C5C=CC(Cl)=C6)=O)C7=C(C(Cl)=CC=C7)F)[H])N4CC8CC8)=C2C=C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.