Fig. 1 · Structure
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Brilaroxazine hydrochloride
5-HT Receptor
Brilaroxazine hydrochloride is a potent modulator of the 5-HT receptor, demonstrating promising therapeutic effects in the management of pulmonary arterial hypertension (PAH). This compound has been shown to mitigate both functional and structural alterations linked to PAH, resulting in marked improvements in pulmonary hemodynamics and right ventricular hypertrophy. Moreover, Brilaroxazine hydrochloride can enhance oxygen saturation levels and reduce elevated pulmonary arterial pressures when administered alongside conventional PAH treatment regimens.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1708960-04-6 |
| Applications | 5-HT Receptor |
| Formula | C22H26Cl3N3O3 |
| Molecular Weight | 486.82 |
| Synonyms | RP5063 hydrochloride |
| SMILES | O=C1NC2=CC(OCCCCN3CCN(CC3)C4=C(Cl)C(Cl)=CC=C4)=CC=C2OC1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.