Fig. 1 · Structure

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Brinzolamide hydrochloride

Carbonic Anhydrase II Inhibitor

Brinzolamide hydrochloride is a selective inhibitor of carbonic anhydrase II with an IC50 of 3.2 nM. It effectively lowers intraocular pressure (IOP) by targeting ciliary carbonic anhydrase II, leading to a reduction in aqueous humor secretion. This compound is particularly valuable for research applications related to glaucoma and other ocular conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 150937-43-2
Applications Carbonic Anhydrase II Inhibitor
Formula C12H22ClN3O5S3
Molecular Weight 419.97
Synonyms AL-4862 hydrochloride
SMILES
O=S(C(S1)=CC2=C1S(N(CCCOC)C[C@@H]2NCC)(=O)=O)(N)=O.Cl[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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