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BRL 54443 maleate

5-HT1E/1F Agonist

BRL 54443 maleate is a potent agonist of the 5-HT1E and 5-HT1F receptors, exhibiting Ki values of 1.1 nM and 0.7 nM, respectively. This compound demonstrates over 30-fold selectivity against other serotonin and dopamine receptors, making it a valuable tool in the study of serotonergic signaling pathways. BRL 54443 maleate is primarily used in research applications focused on anxiety, depression, and other neuropsychiatric disorders where 5-HT receptor modulation is implicated.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1197333-54-2
Applications	5-HT1E/1F Agonist
Formula	C₁₈H₂₂N₂O₅
Molecular Weight	346.38
SMILES	OC1=CC2=C(NC=C2C3CCN(C)CC3)C=C1.O=C(O)/C=C\C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.