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BRM/BRG1 ATP-IN-5

BRM/BRG1 ATP Inhibitor

BRM/BRG1 ATP-IN-5 is a potent inhibitor of the BRG1 and BRM proteins, targeting the BAF complex that plays a crucial role in ATP-dependent chromatin remodeling and gene expression regulation. This compound has demonstrated notable anti-tumor activity, particularly in cancers related to BAF complex dysfunctions. Its unique mechanism offers valuable insights for research into cancer biology and potential therapeutic approaches for BAF-associated malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2468046-57-1
Applications	BRM/BRG1 ATP Inhibitor
Formula	C₂₂H₂₀N₆O₄S₂
Molecular Weight	496.56
SMILES	O=C(C1=CN(S(=O)(C)=O)C=C1)NCC(NC2=NC(C3=CC(C4=CC(N)=NC=C4)=CC=C3)=CS2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.