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BRM/BRG1 ATP-IN-6

BRM/BRG1 ATP Inhibitor

BRM/BRG1 ATP-IN-6 is a selective inhibitor targeting the BRG1/BRM components of the BAF complex, which plays a critical role in chromatin remodeling and gene expression through ATP dependency. This compound exhibits significant anti-tumor activity, particularly in cancers linked to dysregulation of the BAF complex. Its application in research provides insights into chromatin dynamics and potential therapeutic strategies for BAF complex-related malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2468049-60-5
Applications	BRM/BRG1 ATP Inhibitor
Formula	C₂₄H₂₈N₄O₆S₂
Molecular Weight	532.63
SMILES	O=C(C1=CN(C=C1)S(C)(=O)=O)NCC(NC2=NC(C3=CC(CO[C@@H]4CC[C@H](CC4)O)=CC=C3)=CS2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.