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BRM/BRG1 ATP-IN-7

BRM/BRG1 Inhibitor

BRM/BRG1 ATP-IN-7 is a selective inhibitor targeting the SWI/SNF complexes BRM (SMARCA2) and BRG1 (SMARCA4), exhibiting IC50 values of 12 nM and 8 nM, respectively. This compound is valuable for investigating BRM/BRG1-dependent cancers, including non-small cell lung cancer and Ewing sarcoma, as well as certain virus-associated diseases, such as HPV infection. Its potent inhibition provides a useful tool for elucidating the roles of BRM and BRG1 in cancer biology and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2468048-19-1
Applications	BRM/BRG1 Inhibitor
Formula	C₂₃H₂₁N₅O₅S₂
Molecular Weight	511.57
SMILES	O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](CO)C(NC2=NC(C3=CC(C4=CC=NC=C4)=CC=C3)=CS2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.