Fig. 1 · Structure

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BRM/BRG1 ATP-IN-8

BRG1/BRM Inhibitor

BRM/BRG1 ATP-IN-8 is a selective inhibitor targeting the BRG1/BRM ATPase domain, demonstrating potent antitumor activity. By disrupting aberrant chromatin remodeling, this compound effectively induces apoptosis and growth arrest in cancer cells. BRM/BRG1 ATP-IN-8 is well-suited for research into BRG1/BRM-dependent malignancies, including hematological cancers, prostate cancer, breast cancer, and Ewing's sarcoma.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2468046-72-0
Applications BRG1/BRM Inhibitor
Formula C26H23N5O6S2
Molecular Weight 565.62
SMILES
O=C(C1(CC1)C2=NC=CC(C3=CC=CC(C4=CSC(NC(CNC(C5=CN(S(=O)(C)=O)C=C5)=O)=O)=N4)=C3)=C2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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