Fig. 1 · Structure

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BRM/BRG1 ATP Inhibitor-2

BRG1/BRM ATPase Inhibitor

BRM/BRG1 ATP Inhibitor-2 is a selective inhibitor of BRG1 and BRM ATPase activity, targeting the SWI/SNF chromatin remodeling complexes. This compound is valuable for investigating the molecular implications of BAF-related disorders, including cancer and developmental syndromes. Its mechanism of action enables researchers to explore the role of ATP-dependent chromatin remodeling in gene expression regulation and cellular differentiation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2368900-77-8
Applications BRG1/BRM ATPase Inhibitor
Formula C20H20N4O2S2
Molecular Weight 412.53
SMILES
O=C(C1=CN=CC=C1)N[C@@H](CCSC)C(NC2=NC(C3=CC=CC=C3)=CS2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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