Fig. 1 · Structure

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BRM/BRG1 ATP Inhibitor-4

BRG1/BRM Inhibitor

BRM/BRG1 ATP Inhibitor-4 is a specific inhibitor targeting the BRG1 and BRM ATPases. This compound exhibits potent inhibition of the BAF complex, making it valuable for studying its role in oncogenesis and various disorders associated with chromatin remodeling. Research applications include investigating mechanisms of cancer progression and exploring therapeutic strategies for BAF complex-related diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2422030-94-0
Applications BRG1/BRM Inhibitor
Formula C25H32N6O3S
Molecular Weight 496.62
SMILES
O=C(C1=CN(C=C1)C(C)(C)C)NCC(NC2=NC(C3=CC=CC(N4C[C@@H](O[C@@H](C4)C)C)=N3)=CS2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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