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Brodalumab
Brodalumab (AMG 827) is a humanized IgG2 monoclonal antibody targeting the interleukin-17 receptor. This antibody is utilized in research focused on understanding and treating moderate-to-severe plaque psoriasis and rheumatoid arthritis. Brodalumab's mechanism involves blocking the activity of interleukin-17 (IL-17), a cytokine that plays a critical role in mediating inflammatory and immune responses.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1174395-19-7 |
| Molecular Weight | 144060 |
| Synonyms | AMG 827; KHK4827 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.