Bromocriptine

Catalog No.: A60054
Dopamine Receptor Agonist
Bromocriptine is a potent agonist of the dopamine D2 and D3 receptors, exhibiting a high binding affinity with a pKi of 8.05 ± 0.2. This compound is primarily utilized in research to investigate dopaminergic signaling pathways and their implications in various neurological and psychiatric disorders. It is also employed in studies related to endocrine functions, particularly in conditions such as hyperprolactinemia and Parkinson's disease.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBromocriptine is a potent agonist of the dopamine D2 and D3 receptors, exhibiting a high binding affinity with a pKi of 8.05 ± 0.2. This compound is primarily utilized in research to investigate dopaminergic signaling pathways and their implications in various neurological and psychiatric disorders. It is also employed in studies related to endocrine functions, particularly in conditions such as hyperprolactinemia and Parkinson's disease.
Product Information
Catalog NumA60054
FormulaC32H40BrN5O5
Molecular Weight654.59
CAS Number25614-03-3
SMILES[H][C@@]12CC3=C(Br)NC4=CC=CC(C1=C[C@@H](C(N[C@@]5(C(C)C)C(N6[C@@H](CC(C)C)C(N7CCC[C@]7([C@]6(O)O5)[H])=O)=O)=O)CN2C)=C43
SynonymsCB-154 free base
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2