Fig. 1 · Structure
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Brr2-IN-3
Brr2 Inhibitor
Brr2-IN-3 is a potent allosteric inhibitor of the Brr2 helicase. It inhibits helicase activity in a dose-dependent manner, exhibiting an IC50 value of 1.3 μM. This compound is valuable for studying the regulation of RNA splicing and helicase functionality in molecular biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2104030-82-0 |
| Applications | Brr2 Inhibitor |
| Formula | C24H20N4O3S |
| Molecular Weight | 444.51 |
| SMILES | O=C1NC(C(CN1C2=CC=CC(OCC3=CN=CS3)=C2)=CN4CC5=CC=CC=C5)=CC4=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.