Fig. 1 · Structure

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BT44

RET Activator

BT44 is a selective RET activator that effectively penetrates the blood-brain barrier. It demonstrates potential in modulating RET signaling pathways, making it valuable for research focused on neurodegenerative disorders and diabetes mellitus. Its unique properties position BT44 as a significant tool for investigating therapeutic strategies in these complex diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 924759-42-2
Applications RET Activator
Formula C28H27F4N3O4S
Molecular Weight 577.59
SMILES
O=C(N1CCN(CC1)C2=CC(S(=O)(N3CC4=C(CC3)C=CC=C4)=O)=CC=C2OC)C5=CC=C(C=C5C(F)(F)F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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