BTA-188 is a pyridazinyl oxime ether that functions as a potent antiviral agent, specifically targeting rhinoviruses and enterovirus 71. It demonstrates remarkable efficacy with an IC50 of 0.8 nM and IC90 of 11 nM against HRV-2, while effectively inhibiting enterovirus replication with an IC50 of 82 nM and an IC90 of 109 nM. BTA-188 holds potential as a chemotherapeutic candidate for treating infections associated with the Picornaviridae family of viruses.
BTA-188 is a pyridazinyl oxime ether that functions as a potent antiviral agent, specifically targeting rhinoviruses and enterovirus 71. It demonstrates remarkable efficacy with an IC50 of 0.8 nM and IC90 of 11 nM against HRV-2, while effectively inhibiting enterovirus replication with an IC50 of 82 nM and an IC90 of 109 nM. BTA-188 holds potential as a chemotherapeutic candidate for treating infections associated with the Picornaviridae family of viruses.
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