Fig. 1 · Structure
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BTdCPU
HRI Activator
BTdCPU is a potent activator of heme-regulated inhibitor kinase (HRI), which enhances eIF2α phosphorylation and promotes apoptosis specifically in Dexamethasone-resistant cancer cells. This compound is particularly valuable in the investigation of multiple myeloma and serves as a tool for studying mechanisms underlying resistance to therapeutic agents in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1257423-87-2 |
| Applications | HRI Activator |
| Formula | C13H8Cl2N4OS |
| Molecular Weight | 339.20 |
| SMILES | O=C(NC1=CC=C2N=NSC2=C1)NC3=CC=C(C(Cl)=C3)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.