Budesonide-d8

Catalog No.: A64724
Stable Isotope
Budesonide-d8 is a deuterium-labeled analog of Budesonide, which acts primarily as a glucocorticoid receptor agonist. This compound exhibits anti-inflammatory properties essential for the management of asthma and has been shown to reduce lung tumor size, reverse DNA hypomethylation, and modulate mRNA expression of various genes. Budesonide-d8 serves as a valuable tool in pharmacokinetic and metabolic research, providing insights into the pharmacological effects and mechanisms of Budesonide in vivo.
Grouped product items
Size Price Stock Qty
5mg
$690.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBudesonide-d8 is a deuterium-labeled analog of Budesonide, which acts primarily as a glucocorticoid receptor agonist. This compound exhibits anti-inflammatory properties essential for the management of asthma and has been shown to reduce lung tumor size, reverse DNA hypomethylation, and modulate mRNA expression of various genes. Budesonide-d8 serves as a valuable tool in pharmacokinetic and metabolic research, providing insights into the pharmacological effects and mechanisms of Budesonide in vivo.
Product Information
Catalog NumA64724
FormulaC25H26D8O6
Molecular Weight438.58
CAS Number1105542-94-6
SMILESOCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(O2)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C)=O
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