Fig. 1 · Structure

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Buflomedil

Vasoactive agent

Buflomedil is a vasoactive agent primarily functioning as an orally active α1A-adrenoceptor antagonist, with inhibitory constants (Kis) of 4.06 µM for α1A-AR and 6.84 µM for α1B-AR. This compound exhibits vasodilatory properties, making it valuable for investigating peripheral circulatory disorders. Its pharmacological profile supports research aimed at understanding vascular function and the treatment of related cardiovascular conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 55837-25-7
Applications Vasoactive agent
Formula C17H25NO4
Molecular Weight 307.38
SMILES
O=C(C1=C(OC)C=C(OC)C=C1OC)CCCN2CCCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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