Fig. 1 · Structure
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Burapitant
Burapitant (SSR240600) is a modulator of cholinergic transmission, primarily targeting the regulation of acetylcholine release in the limbic and prefrontal regions of the rat striatum. Its biological activity is influenced by interactions between 5-HT2A and 5-HT2C receptors, making it valuable for research in neuropharmacology and behavioral studies. Burapitant may provide insights into the mechanisms underlying cholinergic signaling and its implications for neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 537034-22-3 |
| Formula | C31H35Cl2F6N3O3 |
| Molecular Weight | 682.52 |
| Synonyms | SSR240600 |
| SMILES | CC(C)(C1CCN(CC[C@@]2(C3=CC=C(Cl)C(Cl)=C3)CN(C(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)CCO2)CC1)C(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.