Fig. 1 · Structure
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Burimamide
H2-Receptor Blocker
Burimamide is a selective histamine H2-receptor blocker that effectively inhibits gastric acid secretion stimulated by pentagastrin or gastrin. Additionally, Burimamide exhibits alpha-adrenoceptor blocking activity. When combined with the H1-receptor antagonist Mepyramine, it demonstrates notable anti-inflammatory effects in a rat paw edema model induced by Compound 48/80, making it a valuable tool for research in gastric physiology and inflammation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 34970-69-9 |
| Applications | H2-Receptor Blocker |
| Formula | C9H16N4S |
| Molecular Weight | 212.32 |
| SMILES | S=C(NCCCCC1=CN=CN1)NC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.