Fig. 1 · Structure
Documents & Downloads
Butyzamide
Mpl Activator
Butyzamide is an oral activator of the Mpl receptor, which is vital for thrombopoiesis through its interaction with thrombopoietin (TPO). This compound enhances the phosphorylation of key signaling proteins such as JAK2, STAT3, STAT5, and MAPK, thereby promoting cellular signaling pathways related to platelet production. Butyzamide has been shown to increase platelet levels in mouse xenotransplantation assays, making it a valuable tool for research in hematology and related fields.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1110767-45-7 |
| Applications | Mpl Activator |
| Formula | C29H32Cl2N2O5S |
| Molecular Weight | 591.55 |
| SMILES | CCCOC(C(C)(C)C)C1=CC=CC(C2=CSC(NC(C3=CC(Cl)=C(/C=C(C(O)=O)\C)C(Cl)=C3)=O)=N2)=C1OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.