BV-6

Name: BV-6
Brand: Adooq Bioscience
SKU: A14231
Rating: 100 (1 reviews)

Catalog No.: A14231

dual cIAP and XIAP inhibitor

Product Citations (1)

BV-6 Chemical Structure

CAS NO. 1001600-56-1

BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.

Availability: In stock

Package	Price	Qty
5 mg	$90.00
10 mg	$150.00
25 mg	$300.00
10mM * 1mL in DMSO	$199.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq BV-6

Aneri Shah, .et al. YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation, Cancers (Basel), 2020, Aug 5;12(8):E2188 PMID: 32764479

Biological Activity

BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.

Solubility *

In vitro	DMSO	96 mg/mL (79.62 mM)
	Water	24 mg/mL (19.9 mM)
	Ethanol	Warmed: 96 mg/mL (79.62 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.29 mL	41.47 mL	82.95 mL
0.5 mM	1.66 mL	8.29 mL	16.59 mL
1 mM	0.83 mL	4.15 mL	8.29 mL
5 mM	0.17 mL	0.83 mL	1.66 mL

*The above data is based on the productmolecular weight 1205.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A14231
Actions	Inhibitor
CAS No.	1001600-56-1
Formula	C70H96N10O8
M. Wt	1205.57
Purity	>98%
Synonyms	BV6
SMILES	C[[email protected]@H](C(=O)N[[email protected]@H](C1CCCCC1)C(=O)N2CCC[[email protected]]2C(=O)N[[email protected]@H](C(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)NCCCCCCNC(=O)[[email protected]](C(C5=CC=CC=C5)C6=CC=CC=C6)NC(=O)[[email protected]@H]7CCCN7C(=O)[[email protected]](C8CCCCC8)NC(=O)[[email protected]](C)NC)NC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.