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BY27

Catalog No.: A18972

BET BD2 inhibitor

BY27

BY27 Chemical Structure

CAS NO. 2247236-59-3

BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.7 mL 123.49 mL 246.97 mL
0.5 mM 4.94 mL 24.7 mL 49.39 mL
1 mM 2.47 mL 12.35 mL 24.7 mL
5 mM 0.49 mL 2.47 mL 4.94 mL

*The above data is based on the productmolecular weight 404.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18972
Actions Inhibitor
CAS No. 2247236-59-3
Formula C22H21ClN6
M. Wt 404.9
Purity >98%
Synonyms BY-27, BY 27
SMILES CN1N=CC(C2=CC=C(N3C(CC[[email protected]]4NC5=CC=C(Cl)C=C5)=NN=C3C)C4=C2)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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