BYK 191023 is a selective inhibitor of inducible nitric-oxide synthase (iNOS) that functions as an L-arginine competitive antagonist, exhibiting an IC50 value of 86 nM for iNOS, while displaying significantly higher IC50 values of 17 µM and 162 µM for neuronal (nNOS) and endothelial (eNOS) nitric-oxide synthases, respectively. This compound is vital for studying the role of iNOS in various pathological conditions and demonstrates potential applications in inflammation research and related disease models.
BYK 191023 is a selective inhibitor of inducible nitric-oxide synthase (iNOS) that functions as an L-arginine competitive antagonist, exhibiting an IC50 value of 86 nM for iNOS, while displaying significantly higher IC50 values of 17 µM and 162 µM for neuronal (nNOS) and endothelial (eNOS) nitric-oxide synthases, respectively. This compound is vital for studying the role of iNOS in various pathological conditions and demonstrates potential applications in inflammation research and related disease models.
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