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BzNH-BS

SNIPERs

BzNH-BS is a bifunctional reagent designed to target the cellular inhibitor of apoptosis protein 1 (cIAP1) through its ligand methyl-bestatin (MeBS) and a benzoyl-amide. This compound operates as a SNIPER (Specific and Non-genetic IAP-dependent protein Eraser) to promote the ubiquitination and subsequent degradation of cIAP1. BzNH-BS is useful in studying apoptosis regulation and can be applied in cancer research to explore IAP-related pathways and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2443928-42-3
Applications	SNIPERs
Formula	C₃₅H₅₄N₄O₉
Molecular Weight	674.82
SMILES	N[C@@H]([C@@H](C(N[C@@H](CC(C)C)C(NCCOCCOCCOCCOCCOCCNC(C1=CC=CC=C1)=O)=O)=O)O)CC2=CC=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.