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c-Fms-IN-14

c-Fms inhibitor

c-Fms-IN-14 is a selective inhibitor of the colony stimulating factor 1 receptor (c-Fms), with an IC50 value of 4 nM. This compound demonstrates potent anti-proliferative effects, making it a valuable tool in the study of cancer and autoimmune diseases. Its specific targeting of c-Fms offers opportunities for elucidating the role of macrophages in immune regulation and tumor microenvironments.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1898210-99-5
Applications	c-Fms inhibitor
Formula	C₂₆H₂₄N₆O
Molecular Weight	436.51
SMILES	O=C(NC(C=C1)=CC=C1N(C2=C3N=CN=C2N)C4=C3CCC4)CC5=CC6=C(N(C)C=C6)C=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.