Fig. 1 · Structure

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c-Fms-IN-15

c-Fms Inhibitor

c-Fms-IN-15 is a potent inhibitor of c-Fms kinase with an IC50 of 563 nM. It effectively diminishes FMS signaling, making it a valuable tool for investigating the role of c-Fms in hematopoiesis and tumorigenesis. This compound can be utilized in research focused on macrophage biology and related pathologies, contributing to the understanding of c-Fms-mediated processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3047930-25-3
Applications c-Fms Inhibitor
Formula C29H28F3N7O2
Molecular Weight 563.57
SMILES
O=C(C1=CC(C2=CC=C(NC(NC3=CC=C(N4CCN(C)CC4)C(C(F)(F)F)=C3)=O)C=C2)=NC5=CC=CN=C15)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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