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Biological Activity
c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.66 mL | 123.32 mL | 246.64 mL |
| 0.5 mM | 4.93 mL | 24.66 mL | 49.33 mL |
| 1 mM | 2.47 mL | 12.33 mL | 24.66 mL |
| 5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
*The above data is based on the productmolecular weight 405.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18397 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1628574-50-4 |
| Formula | C21H23N7O2 |
| M. Wt | 405.45 |
| Purity | >98% |
| SMILES | O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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