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c-Fms-IN-9

Catalog No.: A18397

c-FMS inhibitor

c-Fms-IN-9

c-Fms-IN-9 Chemical Structure

CAS NO. 1628574-50-4

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.66 mL 123.32 mL 246.64 mL
0.5 mM 4.93 mL 24.66 mL 49.33 mL
1 mM 2.47 mL 12.33 mL 24.66 mL
5 mM 0.49 mL 2.47 mL 4.93 mL

*The above data is based on the productmolecular weight 405.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18397
Actions Inhibitor
CAS No. 1628574-50-4
Formula C21H23N7O2
M. Wt 405.45
Purity >98%
SMILES O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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