Fig. 1 · Structure
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C12-TLRa
Adjuvant Lipidoid
C12-TLRa is an ionized adjuvant lipid designed to target TLR7/8 receptors within endosomes. This compound plays a critical role in enhancing mRNA delivery as a key structural component of lipid nanoparticles (LNPs). By stimulating innate immune responses, C12-TLRa serves as a valuable tool for the research and development of SARS-CoV-2 mRNA vaccines, contributing to the advancement of immunotherapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3067466-15-0 |
| Applications | Adjuvant Lipidoid |
| Formula | C46H73N5O2 |
| Molecular Weight | 728.10 |
| SMILES | NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3CC4=CC=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.