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C14-Tri-LAN-Gly

NOD1 Agonist

C14-Tri-LAN-Gly is a potent and selective NOD1 agonist that activates the NOD1 pathway, leading to significant modulation of immune responses. This compound has been shown to inhibit cleaved-caspase-3 expression and upregulate A20, suggesting a protective role against hepatocyte apoptosis in models of lethal hepatitis. Additionally, C14-Tri-LAN-Gly influences bone metabolism by inhibiting osteoblastogenesis while promoting osteoclastogenesis, making it a valuable tool for studying immune and bone-related disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1863978-69-1
Applications	NOD1 Agonist
Formula	C₃₀H₅₃N₅O₁₀S
Molecular Weight	675.83
SMILES	CCCCCCCCCCCCCC(N[C@@H](C)C(N[C@@H](C(O)=O)CCC(N[C@H](CSC[C@H](N)C(O)=O)C(NCC(O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.