Fig. 1 · Structure

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C1s-IN-1

C1s Inhibitor

C1s-IN-1 is a selective and competitive inhibitor of the complement component C1s. With a binding affinity characterized by a Kd of 9.8 μM, C1s-IN-1 effectively modulates the classical complement pathway. This compound is primarily used in research focusing on immune regulation and inflammatory processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1016866-61-7
Applications C1s Inhibitor
Formula C16H19N5
Molecular Weight 281.36
SMILES
NC(=N)C1C=NC(=CC=1)N2CCN(CC2)C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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