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C201-0243

FcRn Antagonist

C201-0243 is a potent FcRn antagonist that specifically inhibits the binding of IgG to the neonatal Fc receptor (FcRn) with an IC50 of 3.439 nM. This compound demonstrates significant potential in the study of IgG-mediated autoimmune diseases, making it a valuable tool for researchers investigating the modulation of immune responses and therapeutic strategies for autoimmune conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	931360-60-0
Applications	FcRn Antagonist
Formula	C₁₈H₁₆FN₃O₃
Molecular Weight	341.34
SMILES	O=C(C1=CC2=C(CO)C=NC(C)=C2OC1=N)NC3=CC(F)=CC=C3C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.