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C5 Lenalidomide-6-fluoro

Ligand for E3 Ligase

C5 Lenalidomide-6-fluoro is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound serves as a crucial component in the development of PROTACs, allowing the targeted degradation of specific proteins. Its applications in chemical biology and drug discovery include the modulation of protein levels and the investigation of ubiquitin-proteasome system pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2883539-08-8
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂FN₃O₃
Molecular Weight	277.26
SMILES	O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(N)C=C3C2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.