Fig. 1 · Structure
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C5a Receptor agonist, W5Cha
C5aR Agonist
C5a Receptor agonist, W5Cha, is a selective agonist of the complement C5a receptor (C5aR), exhibiting an EC50 of 0.2 μM. This hexapeptide is derived from the C-terminus of C5a and features specific amino acid modifications that enhance its bioactivity. W5Cha effectively activates the C5aR by interacting with the Arg-206 site, making it a valuable tool for studying C5aR-mediated signaling pathways and related biological processes in inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 144555-23-7 |
| Applications | C5aR Agonist |
| Formula | C45H74N10O7 |
| Molecular Weight | 867.13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.