Fig. 1 · Structure
Documents & Downloads
C5aR-IN-1
C5aR Inhibitor
C5aR-IN-1 is a potent C5a receptor (C5aR) inhibitor, specifically designed to block the activity of the complement component C5a. Elevated levels of C5a are implicated in various autoimmune and inflammatory disorders. This compound is of significant interest for research into inflammation-related diseases, offering potential insights into therapeutic strategies targeting the C5a-C5aR pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2761048-02-4 |
| Applications | C5aR Inhibitor |
| Formula | C36H39F4N3O2 |
| Molecular Weight | 621.71 |
| SMILES | CC1=CC=C(C=C1C(F)(F)F)NC([C@H]2C[C@H]3CCC[C@H]3N([C@H]2C4=CC=C(C=C4)NC5CCCC5)C(C6=C(C=CC=C6C)F)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.