Fig. 1 · Structure
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C791-0064
RAD52 Inhibitor
C791-0064 is a selective inhibitor of RAD52, which acts by binding to the protein and disrupting its single-strand annealing activity. This compound is particularly effective in inhibiting the proliferation of cancer cells exhibiting BRCA2 deficiency, leading to increased DNA damage and subsequent apoptosis. C791-0064 serves as a valuable tool for investigating mechanisms associated with BRCA mutation-related cancers, including breast and ovarian cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 902940-64-1 |
| Applications | RAD52 Inhibitor |
| Formula | C27H34N4O2S |
| Molecular Weight | 478.65 |
| SMILES | O=C(C1=CC(NC(C2=CC=CC=C2S3)=O)=C3C=C1)NCCCN(CC4)CCC4N5CCCCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.