Fig. 1 · Structure
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C8 Ceramine, D-erythro
Drug Derivative
C8 Ceramine, D-erythro, is a ceramide analog characterized by the replacement of the carbonyl group with a methylene group. This compound demonstrates significant pro-apoptotic activity, inducing maximal DNA fragmentation in U937 cells at a concentration of 10 μM within 6 hours of incubation, which is notably more rapid than that of C8 ceramide. C8 Ceramine is utilized in research investigating apoptosis mechanisms and cellular responses to ceramide derivatives.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 170926-06-4 |
| Applications | Drug Derivative |
| Formula | C₂₆H₅₃NO₂ |
| Molecular Weight | 411.70 |
| Synonyms | C8 Ceramine; Ceramine (d18:1/8:0) |
| SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NCCCCCCCC)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.