Fig. 1 · Structure

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Cabazitaxel-d9

Stable Isotope

Cabazitaxel-d9 is a deuterated derivative of Cabazitaxel, a semi-synthetic analog of the natural taxoid 10-deacetylbaccatin III. This compound exhibits potential antineoplastic activity by stabilizing microtubules and inhibiting cancer cell division. Cabazitaxel-d9 serves as a valuable stable isotope for in vivo and in vitro studies, facilitating the investigation of pharmacokinetics and the mechanistic action of Cabazitaxel in cancer research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1383572-19-7
Applications Stable Isotope
Formula C45H48D9NO14
Molecular Weight 844.99
Synonyms XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9
SMILES
CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)OC)C)=O)OC)=C([C@H](C4)OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)C)C)O)OC(C6=CC=CC=C6)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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