Fig. 1 · Structure
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Caf1-IN-1
Caf1 Inhibitor
Caf1-IN-1 (Compound 8j) is a selective inhibitor of ribonuclease Caf1, demonstrating an IC50 of 0.59 µM. Additionally, it functions as a weak inhibitor of poly(A)-specific ribonuclease (PARN) with an IC50 of 23.9 µM. This compound is valuable for studies involving RNA degradation processes and can aid in understanding the role of Caf1 in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1807775-88-7 |
| Applications | Caf1 Inhibitor |
| Formula | C18H23N5O3 |
| Molecular Weight | 357.41 |
| SMILES | O=C1C2=C(N(CCCN(C)C)C(N1O)=O)N=CN2CCC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.