Fig. 1 · Structure
Documents & Downloads
CAI0019
α-Carbonic Anhydrase Inhibitor
CAI0019 is an orally active inhibitor of α-carbonic anhydrase, designed based on the Acetazolamide framework. It demonstrates narrow-spectrum antibiofilm activity, with a MIC50 of 0.094 μM and a MIC90 of 0.39 μM. In a septic peritonitis mouse model, CAI0019 selectively inhibits Enterococcus while sparing most intestinal commensal bacteria, making it a valuable tool for research into antimicrobial therapies and biofilm-associated infections.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2446169-48-6 |
| Applications | α-Carbonic Anhydrase Inhibitor |
| Formula | C11H18N4O3S2 |
| Molecular Weight | 318.42 |
| SMILES | O=C(CCC1CCCCC1)NC2=NN=C(S2)S(=O)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.